J. Cesar Cardenas
J. Cesar Cardenas earned his Ph.D. from the University of Chile, where he studied the mechanism that regulated nuclear Ca2+ under Dr. Enrique Jaimovich’s mentoring. Then he moved to the University of Pennsylvania Medical School where he explored the nuclear localization 1,4,5-trisphosphate receptor (InsP3R) Ca2+channel by using high resolution electron microscopy and cryofracture as a postdoctoral fellow with Dr. Clara Franzini-Armstrong. Motivate in gain a better understanding of the physiological role of the InsP3R he joined Dr. Kevin Foskett’s lab also at UPENN, where he developed a strong interest in the regulation of cellular metabolism and bioenergetics by Ca2+. He was the first to show that basal constitutive low-level Ca2+ signaling by the InsP3R, is essential to maintain the sufficient mitochondrial NADH production to support oxidative phosphorylation in resting cells. In the absence of this calcium signaling, cells become metabolically compromised and a pro-survival AMPK-dependent mTOR-independent autophagy is turned on.
He joined the Department of Anatomy and Cell Developmental Biology Program at the Institute of Biomedical Science of the University of Chile School of Medicine in March of 2012.
Dr. Lovy has extensive knowledge in live cell confocal microscopy of cytoskeletal and mitochondrial dynamics. At present, she is working in understanding how the calcium signal mediated by the InsP3Rs modulate mitochondrial dynamics and is establishing a research line to study the gut microbiome-mitochondria interaction during aging.
Biochemist of the Pontificia Universidad Católica de Valparaíso and Ph.D. in Pharmacology of the University of Chile. I study mechanisms of cell death in cancer and their relation with the metabolic state of the cell and the role of mitochondrial dynamics in tumor progression.
Biochemist from the University of Santiago of Chile and PhD in Biomedical Sciences from the University of Chile. I study the role of ketones in cellular senescence and it impact in cancer.
Medical Technologist from the University of Santiago of Chile and PhD in Biomedical Sciences from the University of Chile, is currently working in the impact of ketogenic diet in dysferlinopathies models
Galdo Bustos Cisterna
Medical Technologist from the University of Chile, working in the endoplasmic reticulum-mitochondrial calcium communication in cancer cell migration.
Ulises Ahumada Castro
Medical Technologist from the University of Chile. Ph.D. student in Biomedical Science Program at the University of Chile. My research focus in the cellular biology and metabolism of cancer and senescence cells, with particular emphasis in endoplasmic reticulum and mitochondria organelle interactions. When I´m not discovering the aging or the cancer cure, I enjoy playing the guitar, music, beers, and knowledge in general.
Medical Technologist and MSc in Biological Sciences from the University of Chile. Assitant Professor of the Medical Technology Department at the University of Chile.
Studying mitochondrial metabolism in neurodegeneration.
Paula Farías Cartes
Biochemistry student from Universidad de Concepcion, working in determine the effect of a new set of IP3R inhibitors in cancer proliferation and invasion. from University of Concepción
Elizabeth Mendoza Atuesta
Biotechnologist student from Universidad Francisco de Paula Santander Cúcuta-Colombia. She is studying the effects of plant extracts in the mitochondrial perform using seahorse technology (XF96e).
Mathias Ignacio Mellado Muñoz
Medical Technology Student at the University of Chile.
Carla Basualto-Alarcon, Current position, Assistant Professor at Aysen University, Chile.
Fabian Jana, Current position, Assistant Professor at Aysen University, Chile.